Adam Ganz’s BBC radio play The Chemistry Between Them looked at the relationship between Margaret Thatcher and Dorothy Hodgkin and what Lisa Jardine called “the extraordinary idea that Hodgkin - who held strong left-wing views throughout her life - should have been a role model for Britain's first female prime minister.”
Based on primary research in the Bodleian library special collections and interviews with people who knew the two women, including Judith Howard FRS, one of Hodgkin’s doctoral students, and the late novelist Nina Bawden, who studied with Thatcher at Somerville College during the First World War, the play looks at the two women through the prism of crystallography. Thatcher learned from Hodgkin working with her on a special project to find the structure of Gramicidin S – a molecule used by the Soviet Union as an antibiotic.
It reconsiders Thatcher as a scientist by formation, who in Hodgkin encountered perhaps for the first time a woman who was a leader of her profession, and who refused to accept the restrictions that marriage or children placed on many women of the period. It suggests that when her former University lecturer became the first British woman to win a Nobel Prize, it made Thatcher think that there need be no limits on her own career,
The play intercuts two time scales, moving between Thatcher’s student years and a conversation that took place at Chequers in the 1980’s as Cruise missiles were being sited in Europe. Hodgkin (then president of the Pugwash group of concerned scientists) was keen to make her former pupil aware of the impossibility of winning a nuclear war and the consequences of a nuclear winter.
The play was reviewed in Nature and was the subject of considerable debate in The Guardian, with Hodgkin’s granddaughter critical of the notion that the two women might be thought of as friends. Jardine, however, compared the play to Michael Frayn’s Copenhagen, saying “They are both, in my view, successful attempts at a kind of bridging between fact and fiction that captures the feelings behind the ideas”.


Margaret Thatcher with Dorothy Hodgkin taken at Somerville College, 1991. Photo by kind permission of Somerville College, University of Oxford